Common miRNA Markers in Adenocarcinomas
hsa-miR-96, hsa-miR-183, hsa-miR-182, and hsa-miR-93 candidates for use as pan-adenocarcinoma miRNA markers...
Posted on: Nov. 05 2025
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Candidate microRNAs for Use as Internal Reference Controls
Three independent panels of microRNAs serving as (i) internal reference controls to verify assay performance, (ii) indicators of hemolysis in plasma or serum samples, and (iii) markers of platelet lysis or contamination during pre-analytical handling
Posted on: Nov. 05 2025
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A potential noninvasive method for characterizing Alzheimer's disease (AD)
This academic article introduces a noninvasive method for characterizing Alzheimer's disease (AD) by analyzing cell-free messenger RNA (cf-mRNA) found in blood plasma.
Posted on: June 16, 2025
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A comprehensive characterization of cfRNA
This Nature Communications article presents a groundbreaking study on cell-free RNA (cfRNA) as a novel biomarker for cancer detection. The researchers comprehensively characterized cfRNA in both cancer and non-cancer patients, leading to the discovery of so-called "dark channel biomarker" (DCB) genes.
Posted on: June 16, 2025
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Pioneering Detection of Tumor Messenger RNA in Melanoma
A landmark 1999 study by Kopreski et al. published in Clinical Cancer Research demonstrated the detection of tumor messenger RNA in the serum of patients with malignant melanoma. The researchers successfully demonstrated the presence of amplifiable human mRNA, specifically tyrosinase mRNA, in the serum of melanoma patients, a significant finding given the presumed instability of mRNA in blood.
Posted on: June 16, 2025
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